Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035708 | 0.82 | CES2 (0.55) | KDM4EPARP1TSHRCTNNB1FBP1 | |
| SCHEMBL11756446 | 0.82 | TP53 (0.56) | CA12CA1CA2CA6CA9 | |
| SCHEMBL1277041 | 0.81 | PARP1 (0.50) | KDM4EPARP1TSHRCTNNB1 | |
| SCHEMBL5619554 | 0.81 | PARP1 (0.50) | ALDH1A1PARP1 | |
| SCHEMBL339923 | 0.81 | ERCC5 (0.58) | ALDH1A1PARP1 | |
| SCHEMBL8980284 | 0.81 | PBRM1 (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL28415551 | 0.81 | CES2 (0.66) | ALDH1A1KDM4ETSHRCES2CES1 | |
| SCHEMBL8779987 | 0.79 | ERCC5 (0.61) | ALDH1A1KMO | |
| SCHEMBL280150 | 0.79 | MAPT (0.54) | ALDH1A1KDM4EALOX15TSHRCES2 | |
| SCHEMBL3863357 | 0.78 | LOXL2 (0.51) | ALDH1A1TSHRKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6157579-A | — | — | None | — | — | JP | disclosed |
| CN-116987061-A | 4-methyl quinazoline derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-11-03 | — | — | CN | disclosed |
| CN-113853662-A | Solid electrolytic capacitor | 阿维科斯公司 | 2021-12-28 | — | — | CN | disclosed |
| US-10617759-B2 | Light-stimulated release of cargo from oligonucleotides | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190008963-A1 | LIGHT-STIMULATED RELEASE OF CARGO FROM OLIGONUCLEOTIDES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2019-01-10 | — | — | US | disclosed |
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | disclosed |
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| JP-H06157579-A | NEW GLYCOSIDE AND UV ABSORBING AND SCATTERING AGENT CONTAINING THE SAME | SATO TAKESHI | 1994-06-03 | — | — | JP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617759-B2 | Light-stimulated release of cargo from oligonucleotides | DCLRE1B, CLTA, EEA1 | CA12 4082/4885CA1 4450/4885CA2 4358/4885 |
| US-20190008963-A1 | LIGHT-STIMULATED RELEASE OF CARGO FROM OLIGONUCLEOTIDES | DCLRE1B, CLTA, EEA1 | CA12 4082/4885CA1 4450/4885CA2 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.