SCHEMBL8980324

SCHEMBL8980324

O=C(O)c1cc(Cl)cc2scnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
DAO P14920 3/20 0.41
CYP3A4 P08684 1/20 0.41
KDM4E B2RXH2 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HKDC1 Q2TB90 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592514 0.79 XDH (0.41) XDHSLC22A12DAOKDM4ENPC1
SCHEMBL30981544 0.77 HPGD (0.41) KDM4ENPC1RAB9ATDP1ALDH1A1
SCHEMBL3852220 0.74 ALDH1A1 (0.46) CYP3A4KDM4ENPC1RAB9AL3MBTL1
SCHEMBL30361210 0.73 ALDH1A1 (0.41) XDHSLC22A12DAOKDM4ENPC1
SCHEMBL262049 0.71 ALDH1A1 (0.44) XDHSLC22A12DAOCYP3A4KDM4E
SCHEMBL27185462 0.71 DAO (0.40) XDHSLC22A12DAOKDM4ENPC1
SCHEMBL18876146 0.71 HSD11B1 (0.35) NPC1RAB9AALDH1A1HSD11B1MEN1
Ammonia Solution, Strong SCHEMBL28632131 0.69 HSD11B1 (0.34) NPC1RAB9AALDH1A1HSD11B1
SCHEMBL30696060 0.68 XDH (0.41) XDHSLC22A12DAOKDM4ENPC1
SCHEMBL4420731 0.67 NPC1 (0.58) XDHSLC22A12DAOKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed