Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595095 | 0.80 | GPR139 (0.55) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10101151 | 0.80 | KMT2A (0.56) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8387484 | 0.80 | GPR139 (0.55) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL12642206 | 0.80 | GPR139 (0.62) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL19034783 | 0.78 | GPR139 (0.54) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8980470 | 0.77 | GPR139 (0.52) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL1055212 | 0.77 | GPR139 (0.52) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8123492 | 0.77 | KMT2A (0.54) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14417102 | 0.77 | GPR139 (0.52) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11264480 | 0.77 | KMT2A (0.60) | GPR139KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710228-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003280-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N3S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1995-02-02 | — | — | WO | disclosed |