Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646379 | 0.89 | NAAA (0.56) | KDM4EALDH1A1CDK1NAAATRPA1 | |
| SCHEMBL18646048 | 0.86 | NAAA (0.65) | KDM4EALDH1A1CDK1NAAAALOX5 | |
| SCHEMBL18645568 | 0.85 | NAAA (0.72) | KDM4ECDK1NAAAALOX5PTGS2 | |
| SCHEMBL8980647 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| Gentisic Acid Ethanolamide SCHEMBL1179368 | 0.80 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| Gentisic Acid Ethanolamide SCHEMBL29379843 | 0.80 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL12722670 | 0.80 | POLB (0.57) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980561 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980687 | 0.78 | CDK1 (0.82) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980880 | 0.78 | KDM4E (0.69) | KDM4EALDH1A1MAPTCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |