Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646048 | 0.91 | NAAA (0.65) | NAAACDK1ALOX5PTGS2KDM4E | |
| SCHEMBL18645568 | 0.89 | NAAA (0.72) | NAAACDK1ALOX5PTGS2KDM4E | |
| SCHEMBL8980583 | 0.89 | KDM4E (0.55) | NAAATRPA1CDK1ALOX5PTGS2 | |
| SCHEMBL18645554 | 0.82 | NAAA (0.57) | NAAAPOLBTHRBRECQLTDP1 | |
| SCHEMBL18614057 | 0.81 | HSP90AA1 (0.56) | NAAAPOLBTHRBRECQLTDP1 | |
| SCHEMBL9363837 | 0.81 | ALOX5 (0.58) | NAAAPOLBTHRBRECQLTDP1 | |
| SCHEMBL18614004 | 0.78 | HSP90AA1 (0.56) | NAAAPOLBTHRBRECQLTDP1 | |
| SCHEMBL646876 | 0.76 | CA12 (0.65) | POLBTRPA1PTGS2KDM4EALDH1A1 | |
| SCHEMBL1238119 | 0.76 | NAAA (0.76) | NAAAPOLBL3MBTL1ALOX5KDM4E | |
| SCHEMBL925372 | 0.75 | TRPA1 (0.57) | POLBTRPA1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980755-B2 | LRH-1 modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-20 | — | — | US | disclosed |
| WO-2017044889-A1 | LRH-1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10980755-B2 | LRH-1 modulators | NR1H4, NR1H2, NR1H3 | NAAA 3812/4885POLB 4347/4885THRB 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.