Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636633 | 0.84 | MAPT (0.41) | KDM4EALDH1A1DRD2RAB9AKMT2A | |
| SCHEMBL8368757 | 0.83 | KDM4E (0.35) | KDM4EHSD17B10 | |
| SCHEMBL8640110 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAMEN1NPC1 | |
| SCHEMBL8980601 | 0.83 | APP (0.39) | CYP19A1ALDH1A1PRMT5WDR77MEN1 | |
| SCHEMBL9174068 | 0.83 | MEN1 (0.43) | CYP19A1KDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL8573189 | 0.83 | MAOB (0.40) | CYP19A1NOTUMALDH1A1PKMTDP2 | |
| SCHEMBL8980607 | 0.81 | PARP1 (0.39) | ALDH1A1L3MBTL1NPC1PKMRAB9A | |
| SCHEMBL8575144 | 0.80 | MAPT (0.44) | CYP19A1KDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL7249895 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1DRD2NPC1PKM | |
| SCHEMBL8654922 | 0.80 | CASP3 (0.40) | DRD2PRMT5WDR77HTR2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |