Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | HTR1A | P08908 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | MTOR | P42345 | 1/20 | 0.78 |
| ▸ | RAB9A | P51151 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | DRD4 | P21917 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011055 | 0.89 | CYP2D6 (0.88) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL29786717 | 0.89 | ADRA1A (1.00) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL19568202 | 0.89 | CYP2D6 (0.86) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL18211393 | 0.89 | HTR1A (0.86) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL4014204 | 0.89 | ADRA1A (1.00) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL29387395 | 0.88 | CYP2D6 (1.00) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL2640211 | 0.88 | CYP2D6 (1.00) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| Hydrochloric Acid SCHEMBL7041045 | 0.87 | CYP2D6 (0.98) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL27775854 | 0.85 | HTR1A (0.61) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL13314093 | 0.80 | HTR1A (0.75) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281090-A1 | Microfluidic Chemical Reaction Circuits | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-11-13 | — | — | US | claimed |
| US-9556081-B2 | Device and method for the production of radiochemical compounds | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20160115092-A1 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2016-04-28 | — | — | US | disclosed |
| US-9260354-B2 | Device and method for the production of radiochemical compounds | ABX ADVANCED CHEMICAL COMPOUNDS GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| US-20150133650-A1 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | GESIM-GESELLSCHAFT FUER SILIZIUM-MIKROSYSTEME MBH (DE) | 2015-05-14 | — | — | US | disclosed |
| US-8980184-B2 | Device and method for the preparation of radiochemical compounds | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20130144051-A1 | Device And Method For The Preparation Of Radiochemical Compounds | GESIM-GESELLSCHAFT FUER SILIZIUM-MIKROSYSTEME MBH (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-2585211-A2 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | ABX Advanced Biochemical Compounds GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-8206593-B2 | Adapted for on-chip solvent exchange; synthesis of radiopharmaceuticals such as FDG (fludeoxyglucose F18) for example | FLUIDIGM CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| WO-2012041305-A2 | DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |
| US-20080281090-A1 | Microfluidic Chemical Reaction Circuits | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1838431-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | California Institute of Technology (US) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006071470-A2 | MICROFLUIDIC DEVICES WITH CHEMICAL REACTION CIRCUITS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-07-06 | — | — | WO | disclosed |
| EP-1667794-A2 | SYSTEM AND METHOD FOR SYNTHESIS OF MOLECULAR IMAGING PROBES INCLUDING FDG | Molecular Technologies Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050232387-A1 | Microfluidic apparatus and method for synthesis of molecular imaging probes | MOLECULAR TECHNOLOGIES, INC. | 2005-10-20 | — | — | US | disclosed |
| US-20050232861-A1 | Microfluidic apparatus and method for synthesis of molecular imaging probes including FDG | MOLECULAR TECHNOLOGIES | 2005-10-20 | — | — | US | disclosed |
| US-20040258615-A1 | System and method for synthesis of molecular imaging probes including FDG | MOLECULAR TECHNOLOGIES, INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004093652-A2 | SYSTEM AND METHOD FOR SYNTHESIS OF MOLECULAR IMAGING PROBES INCLUDING FDG | MOLECULAR TECHNOLOGIES, INC. (US) | 2004-11-04 | — | — | WO | disclosed |