Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 3/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | DRD4 | P21917 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387395 | 1.00 | CYP2D6 (1.00) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| Hydrochloric Acid SCHEMBL7041045 | 0.99 | CYP2D6 (0.98) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL8011055 | 0.93 | CYP2D6 (0.88) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL29786717 | 0.92 | ADRA1A (1.00) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL19568202 | 0.92 | CYP2D6 (0.86) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL4014204 | 0.92 | ADRA1A (1.00) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL18211393 | 0.92 | HTR1A (0.86) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL898147 | 0.88 | CYP2D6 (0.79) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| Hydrochloric Acid SCHEMBL7041048 | 0.85 | CYP2D6 (0.73) | CYP2D6TSHRCYP2C19MTORRAB9A | |
| SCHEMBL84137 | 0.83 | HTR1A (0.72) | CYP2D6TSHRCYP2C19MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140608-A1 | NEUROPSYCHOPHARMACOLOGICAL TREATMENT REGIMES FOR TREATING PSYCHOLOGICAL DISORDERS | KEATING CHARLOTTE L (AU) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011140607-A1 | A METHOD OF TREATMENT AND DIAGNOSIS | KEATING CHARLOTTE L (AU) | 2011-11-17 | — | — | WO | disclosed |
| US-20060258667-A1 | Method for improving respiratory function and inhibiting muscular degeneration | NIH-DEITR | 2006-11-16 | — | — | US | disclosed |
| US-7071194-B2 | Method for improving respiratory function and inhibiting muscular degeneration | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2006-07-04 | — | — | US | disclosed |
| US-20030139422-A1 | Method for improving respiratory function and inhibiting muscular degeneration | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2003-07-24 | — | — | US | disclosed |
| WO-2001068073-A2 | METHOD FOR IMPROVING RESPIRATORY FUNCTION AND INHIBITING MUSCULAR DEGENERATION | CHILDREN'S MEDICAL CENTER CORPORATION, THE (US) | 2001-09-20 | — | — | WO | disclosed |