SCHEMBL4014204

SCHEMBL4014204

COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 3/20 1.00
HTR1A P08908 3/20 1.00
CYP2D6 P10635 2/20 1.00
CYP3A4 P08684 1/20 1.00
MEN1 O00255 1/20 0.98
ALDH1A1 P00352 1/20 0.98
BLM P54132 1/20 0.98
PMP22 Q01453 1/20 0.98
KMT2A Q03164 1/20 0.98
TSHR P16473 1/20 0.85
CYP2C19 P33261 1/20 0.85
MTOR P42345 1/20 0.85
RAB9A P51151 1/20 0.85
HIF1A Q16665 1/20 0.85
DRD4 P21917 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29786717 1.00 ADRA1A (1.00) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL8011055 0.93 CYP2D6 (0.88) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL19568202 0.93 CYP2D6 (0.86) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL18211393 0.93 HTR1A (0.86) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL29387395 0.92 CYP2D6 (1.00) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL2640211 0.92 CYP2D6 (1.00) ADRA1AHTR1ACYP2D6CYP3A4MEN1
Hydrochloric Acid SCHEMBL7041045 0.91 CYP2D6 (0.98) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL898147 0.89 CYP2D6 (0.79) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL13314093 0.86 HTR1A (0.75) ADRA1AHTR1ACYP2D6CYP3A4MEN1
SCHEMBL14761343 0.84 HTR1A (0.73) ADRA1AHTR1ACYP2D6CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 WO claimed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 US claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
CN-120053688-A Nanometer medicine for regulating tumor immune microenvironment, preparation method, composition and application thereof 中山大学 2025-05-30 CN claimed
CN-114821705-B Human head posture estimation method based on classification before regression 南京邮电大学 2025-02-18 CN claimed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 US claimed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 US claimed
CN-118101957-A High-performance rendering sub-pixel image compression method and device 上海通途半导体科技有限公司 2024-05-28 CN claimed
CN-117763638-A Electrode loss numerical simulation method for metallized polypropylene film capacitor 昆明理工大学 2024-03-26 CN claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
US-11559785-B2 Method for separation of radioactive sample using monolithic body on microfluidic chip THE UNIVERSITY OF HULL (GB) 2023-01-24 US claimed
CN-109154671-B Radioactivity detection 赫尔大学 2022-10-04 CN claimed
CN-113162042-B MPPF capacitor failure assessment method in MMC system based on band energy 重庆大学 2022-09-09 CN claimed
US-11369955-B2 Method and apparatus for the analysis of compounds THE UNIVERSITY OF HULL (GB) 2022-06-28 US claimed
US-20220146492-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY SHINE IAN BASIL (US) 2022-05-12 US claimed
CN-114410765-A Application of miRNA molecular marker in schizophrenia detection 上海大学 2022-04-29 CN claimed
CN-114203317-A Method for loading spent fuel assemblies in pressurized water reactor core 中国核动力研究设计院 2022-03-18 CN claimed
EP-3953000-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY Shine, Ian Basil (US) 2022-02-16 EP claimed
EP-1363890-A2 MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF Millennium Pharmaceuticals, Inc. (US) 2003-11-26 EP claimed
WO-2002062766-A2 MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-08-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12016935-B2 Methods for detecting CCR2 receptors CCR2, CCR1, CCR5 ADRA1A 598/4885HTR1A 1059/4885CYP2D6 2536/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 ADRA1A 95/4885HTR1A 4/4885CYP2D6 928/4885
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR5 ADRA1A 598/4885HTR1A 1059/4885CYP2D6 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.