SCHEMBL8982190

SCHEMBL8982190

Cc1cccc2nc(-c3cc4ccccc4o3)oc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.45
MAOA P21397 5/20 0.45
CD74 P04233 1/20 0.44
MIF P14174 1/20 0.44
MAPT P10636 4/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
USP2 O75604 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8982216 0.84 NPC1 (0.52) CD74MIFMAPTNPC1RAB9A
SCHEMBL3132729 0.79 NPC1 (0.61) MAOBMAOACD74MIFMAPT
SCHEMBL13700939 0.75 CD74 (0.62) CD74MIFMAPTNPC1RAB9A
SCHEMBL13620846 0.75 MAPT (0.58) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL3131278 0.75 KDM4E (0.63) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL13620845 0.74 ALDH1A1 (0.46) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL2587399 0.74 DHODH (0.58) MAOBMAOANPC1RAB9AKDM4E
SCHEMBL14266185 0.74 ALOX5 (0.57) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL13633926 0.73 NPC1 (0.45) MAOBMAOACD74MIFMAPT
SCHEMBL8783390 0.72 SIRT6 (0.53) MAPTNPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722714-A2 Benzoxazole derivatives, the use thereof as sunscreens and cosmetic compositions containing them 3V SIGMA S.p.A (IT) 1996-07-24 EP claimed
WO-2023199630-A1 POLYMERIZABLE COMPOUND AND MIXED COMPOSITION 住友化学株式会社 2023-10-19 WO disclosed
EP-0722714-A2 Benzoxazole derivatives, the use thereof as sunscreens and cosmetic compositions containing them 3V SIGMA S.p.A (IT) 1996-07-24 EP disclosed
US-5518713-A RADIATION RESISTANCE FOR SKINS 3V INC. (US) 1996-05-21 US disclosed