Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451238 | 0.87 | ALDH1A1 (0.55) | SMN1; SMN2RAB9AL3MBTL1LMNAHTT | |
| SCHEMBL10127207 | 0.86 | KMT2A (0.57) | SMN1; SMN2RAB9ANPC1L3MBTL1LMNA | |
| SCHEMBL236821 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1LMNAMAPT | |
| SCHEMBL11170817 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL9195477 | 0.81 | LMNA (0.56) | SMN1; SMN2RAB9ANPC1L3MBTL1LMNA | |
| SCHEMBL1808069 | 0.81 | ABCB11 (0.56) | SMN1; SMN2LMNAMAPTKMT2AMMP2 | |
| SCHEMBL11479523 | 0.81 | ESR1 (0.45) | SMN1; SMN2L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL11165524 | 0.81 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1L3MBTL1LMNA | |
| SCHEMBL11208076 | 0.81 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1L3MBTL1LMNA | |
| SCHEMBL15243078 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536562-B1 | Fluoro-polymers containing blocked phenols, process for their preparation and curable compositions containing them | BAYER AG (DE) | 1996-05-08 | — | — | EP | disclosed |
| EP-0536562-A1 | Fluoro-polymers containing blocked phenols, process for their preparation and curable compositions containing them | BAYER AG (DE) | 1993-04-14 | — | — | EP | disclosed |