Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451238 | 0.90 | ALDH1A1 (0.55) | LMNAKMT2ATSHRMMP2MMP9 | |
| SCHEMBL1598705 | 0.84 | LMNA (0.57) | LMNAKMT2AMMP2MMP9MMP8 | |
| SCHEMBL8536318 | 0.82 | CA2 (0.55) | LMNACYP1A2KMT2ATSHRTDP1 | |
| SCHEMBL6894576 | 0.82 | GAA (0.51) | LMNAKMT2ATSHRMMP2MMP9 | |
| SCHEMBL8983166 | 0.81 | SMN1; SMN2 (0.51) | LMNAKMT2ATDP1MMP2MMP9 | |
| SCHEMBL2132487 | 0.81 | TDP1 (0.50) | CYP3A4MAOAKMT2ATSHRTDP1 | |
| SCHEMBL23758132 | 0.81 | TDP1 (0.41) | LMNACYP1A2CYP3A4MAOAKMT2A | |
| SCHEMBL11597793 | 0.81 | KMT2A (0.50) | LMNAKMT2ATSHRMMP2MMP9 | |
| SCHEMBL1788818 | 0.81 | KMT2A (0.49) | LMNACYP1A2KMT2ATDP1MMP2 | |
| SCHEMBL24418978 | 0.81 | KMT2A (0.49) | LMNAKMT2AMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2023-02-16 | — | — | US | disclosed |
| EP-0482508-B1 | Biscationic azo dyes and their intermediates | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0482508-A1 | Biscationic azo dyes and their intermediates | BASF Aktiengesellschaft (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4942242-A | ANTICHOLESTEROL AGENTS | KOJIMA TADAO (JP) | 1990-07-17 | — | — | US | disclosed |
| US-4798838-A | ANTICOAGULANTS, ANTICHOLESTEROL AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-17 | — | — | US | disclosed |
| US-4795753-A | Certain pyridyl or imidazol-1-yl-alkyleneoxy-(or amino)phenoxy-alkanoates having lipid lowering activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0130077-A2 | Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051773-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TLR2, TLR3, TLR4 | LMNA 3441/4885CYP1A2 4081/4885CYP3A4 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.