Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342330 | 0.87 | ALDH1A1 (0.62) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL2724487 | 0.85 | ALDH1A1 (0.56) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL8956742 | 0.85 | SHBG (0.54) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL27917766 | 0.85 | SHBG (0.54) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL2721684 | 0.85 | MEN1 (0.56) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL4313107 | 0.81 | CYP11B2 (0.46) | SHBGERCC5FEN1CES2CES1 | |
| SCHEMBL571251 | 0.80 | CTBP2 (0.56) | SHBGCES1ALDH1A1CTBP2PKM | |
| SCHEMBL1515732 | 0.80 | ERCC5 (0.59) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL31365969 | 0.79 | CTBP2 (0.58) | SHBGALDH1A1CTBP2PKMRAB9A | |
| SCHEMBL29987169 | 0.79 | ERCC5 (0.74) | ERCC5FEN1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |