SCHEMBL8984622

SCHEMBL8984622

CC(=O)Cc1cccc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.54
IDO1 P14902 2/20 0.52
TAAR1 Q96RJ0 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 2/20 0.45
AKR1B1 P15121 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
P2RX7 Q99572 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PTPRC P08575 1/20 0.43
PTPRG P23470 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
AKR1B10 O60218 1/20 0.41
UGT1A9 O60656 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265672 0.85 CTBP2 (0.55) PNMTIDO1KMT2AL3MBTL1ALDH1A1
SCHEMBL30785266 0.84 L3MBTL1 (0.41) PNMTIDO1SMN1; SMN2P2RX7L3MBTL1
SCHEMBL1699581 0.84 L3MBTL1 (0.41) PNMTIDO1SMN1; SMN2P2RX7L3MBTL1
SCHEMBL6194277 0.83 PNMT (0.58) PNMTIDO1TAAR1MEN1KMT2A
SCHEMBL24173599 0.82 ANO1 (0.43) TAAR1MEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL14691047 0.82 P2RX7 (0.45) AKR1B1SMN1; SMN2P2RX7L3MBTL1NPC1
SCHEMBL5241360 0.82 CYP1A2 (0.48) KMT2AAKR1B1L3MBTL1NPC1RAB9A
SCHEMBL13235696 0.82 IAPP (0.56) PNMTIDO1TAAR1MEN1KMT2A
SCHEMBL30287815 0.82 P2RX7 (0.45) AKR1B1SMN1; SMN2P2RX7L3MBTL1NPC1
SCHEMBL2547244 0.81 AKR1B1 (0.63) PNMTIDO1TAAR1TSHRAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115436507-A Method for detecting content of 3,4' -dichloropropiophenone 山东京博生物科技有限公司 2022-12-06 CN claimed
CN-100494150-C Preparation and application of indandione derivative raticide and ammonium or sodium salt thereof DALIAN LAB CHEMICAL CO LTD (CN) 2009-06-03 CN claimed
CN-101407469-A Preparation method of bupropion hydrochloride ZHEJIANG JINGXIN PHARMACEUTICA (CN) 2009-04-15 CN claimed
CN-1803752-A Preparation and application of indandione derivative raticide and ammonium or sodium salt thereof DALIAN LAB CHEMICAL CO LTD (CN) 2006-07-19 CN claimed
CN-115436507-B Method for detecting content of 3, 4' -dichlorophenone acetone 山东京博生物科技有限公司 2024-08-30 CN disclosed
CN-116535434-A High-temperature corrosion inhibitor for oil and gas field and preparation method thereof 西南石油大学 2023-08-04 CN disclosed
CN-115436507-A Method for detecting content of 3,4' -dichloropropiophenone 山东京博生物科技有限公司 2022-12-06 CN disclosed
CN-100560563-C The synthetic method of BUPROPIONE HCl ZHEJIANG APELOA PHARMACEUTICAL (CN) 2009-11-18 CN disclosed
CN-100494150-C Preparation and application of indandione derivative raticide and ammonium or sodium salt thereof DALIAN LAB CHEMICAL CO LTD (CN) 2009-06-03 CN disclosed
CN-101407469-A Preparation method of bupropion hydrochloride ZHEJIANG JINGXIN PHARMACEUTICA (CN) 2009-04-15 CN disclosed
CN-101407469-A Preparation method of bupropion hydrochloride ZHEJIANG JINGXIN PHARMACEUTICA (CN) 2009-04-15 CN disclosed
CN-101088985-A Amfebutamone hydrochloride synthesizing process ZHEJIANG PULUO MEDICINE SCI TE (CN) 2007-12-19 CN disclosed
CN-1803752-A Preparation and application of indandione derivative raticide and ammonium or sodium salt thereof DALIAN LAB CHEMICAL CO LTD (CN) 2006-07-19 CN disclosed
US-5578737-A SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-11-26 US disclosed
US-5387725-A Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed
EP-0611366-A1 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1994-08-24 EP disclosed
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO disclosed