Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826468 | 0.79 | HTR2A (0.65) | MEN1KMT2AMAPTPKMCTSK | |
| SCHEMBL8415706 | 0.77 | ACE (0.46) | MEN1KMT2AMAPTPKMCTSK | |
| SCHEMBL8418352 | 0.77 | ACE (0.46) | MEN1KMT2AMAPTPKMCTSK | |
| SCHEMBL28268218 | 0.76 | APAF1 (0.49) | MEN1KMT2AMAPTKDM4EAPAF1 | |
| SCHEMBL27763685 | 0.76 | HTR2A (0.49) | MEN1KMT2AMAPTPKMCTSK | |
| SCHEMBL6394945 | 0.74 | GPR84 (0.54) | MEN1KMT2AMAPTPKMHTR2A | |
| SCHEMBL27763691 | 0.74 | MGAM (0.52) | MEN1KMT2AMAPTPKMCTSK | |
| SCHEMBL31285794 | 0.74 | KDM4E (0.60) | MEN1KMT2AMAPTACEKDM4E | |
| SCHEMBL1878736 | 0.74 | GPR84 (0.53) | MEN1KMT2AMAPTPKMHTR2A | |
| SCHEMBL27777642 | 0.74 | GPR84 (0.56) | MEN1KMT2AMAPTPKMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714909-A1 | Composition for prophylaxis or treatment of pulmonary circulatory diseases | Takeda Chemical Industries, Ltd. (JP) | 1996-06-05 | — | — | EP | disclosed |