SCHEMBL1878736

SCHEMBL1878736

CC(NCC(=O)O)c1c[nH]c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.53
FFAR1 O14842 2/20 0.50
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 3/20 0.49
GAA P10253 3/20 0.49
MAPT P10636 2/20 0.49
MGAM O43451 2/20 0.49
SI P14410 2/20 0.49
MGAM2 Q2M2H8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
POLB P06746 2/20 0.49
PKM P14618 1/20 0.49
APAF1 O14727 1/20 0.49
RECQL P46063 1/20 0.49
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10968796 0.83 PKM (0.55) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL10971099 0.82 TACR1 (0.47) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL10890538 0.82 MAPT (0.45) GPR84FFAR1HTR2AHTR2CHTR2B
Succinic Acid SCHEMBL31447438 0.82 ADAM17 (0.54) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL6394945 0.81 GPR84 (0.54) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL4666383 0.80 GPR84 (0.60) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL3656418 0.78 HTR2A (0.62) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL29611986 0.78 HTR2A (0.62) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL6982959 0.78 HTR2A (0.62) GPR84FFAR1HTR2AHTR2CHTR2B
SCHEMBL6986747 0.78 HTR2A (0.62) GPR84FFAR1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12589171-B2 177-Lu labeled peptide for site-specific uPAR-targeting TRT INNOVATIONS APS (DK) 2026-03-31 US claimed
EP-4448020-B1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS CURASIGHT AS (DK) 2026-02-04 EP claimed
EP-4678194-A1 THERAPEUTIC APPLICATION OF 64CU-LABELLED CONJUGATES FOR SITE-SPECIFIC UPAR-TARGETING Curasight A/S (DK) 2026-01-14 EP claimed
EP-4651912-A1 RADIONUCLIDE LABELLED PEPTIDE CONJUGATE FOR SITE-SPECIFIC UPAR-TARGETING Curasight A/S (DK) 2025-11-26 EP claimed
US-20250319215-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS (HNSCCS) CURASIGHT AS (DK) 2025-10-16 US claimed
US-12409240-B2 Positron emitting radionuclide labeled peptides for human uPAR PET imaging CURASIGHT A/S (DK) 2025-09-09 US claimed
US-20250049971-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS CURASIGHT A/S (DK) 2025-02-13 US claimed
WO-2024153756-A1 RADIONUCLIDE LABELLED PEPTIDE CONJUGATE FOR SITE-SPECIFIC UPAR-TARGETING CURASIGHT A/S (DK) 2024-07-25 WO claimed
EP-3590542-B1 POSITRON EMITTING RADIONUCLIDE LABELED PEPTIDES FOR HUMAN UPAR PET IMAGING CURASIGHT AS (DK) 2024-01-03 EP claimed
EP-4197561-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS Curasight A/S (DK) 2023-06-21 EP claimed
US-20220202966-A1 POSITRON EMITTING RADIONUCLIDE LABELED PEPTIDES FOR HUMAN UPAR PET IMAGING CURASIGHT A/S (DK) 2022-06-30 US claimed
US-11311637-B2 Positron emitting radionuclide labeled peptides for human uPAR PET imaging CURASIGHT A/S (DK) 2022-04-26 US claimed
EP-1621546-B1 Peptide ligands specific to immonoglobulins TECNOGEN SPA (IT) 2008-10-29 EP claimed
US-7026282-B1 Peptide antagonists of the human urokinase receptor and method for selecting them Cancerforskningsfonden AF 1989 (Fonden Til Fremme AF Exsperimentel Cancerforskning) (DK) 2006-04-11 US claimed
EP-1621546-A1 Peptide ligands specific to immonoglobulins TECNOGEN S.C.P.A. (IT) 2006-02-01 EP claimed
WO-2000001802-A2 PEPTIDE ANTAGONISTS OF THE HUMAN UROKINASE RECEPTOR AND METHOD FOR SELECTING THEM CANCERFORSKNINGSFONDEN AF 1989 (FONDEN TIL FREMME AF EKSPERIMENTEL CANCERFORSKNING) (DK) 2000-01-13 WO claimed
US-12589171-B2 177-Lu labeled peptide for site-specific uPAR-targeting TRT INNOVATIONS APS (DK) 2026-03-31 US disclosed
US-20260069728-A1 MULTI-TARGETING COMPOUND AND USE THEREOF CHENGDU SHETAI MEDICAL TECHNOLOGY CO., LTD. (CN) 2026-03-12 US disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed
EP-0061768-B1 N-AMIDO SUBSTITUTED DIPEPTIDES USV PHARMACEUTICAL CORPORATION (US) 1986-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589171-B2 177-Lu labeled peptide for site-specific uPAR-targeting LNPEP, XPNPEP2, PLAUR GPR84 674/4885FFAR1 1754/4885HTR2A 120/4885
US-20220202966-A1 POSITRON EMITTING RADIONUCLIDE LABELED PEPTIDES FOR HUMAN UPAR PET IMAGING PLAUR, PLAU, SERPINE1 GPR84 384/4885FFAR1 488/4885HTR2A 3295/4885
US-12409240-B2 Positron emitting radionuclide labeled peptides for human uPAR PET imaging PLAUR, PLAU, SERPINE1 GPR84 384/4885FFAR1 488/4885HTR2A 3295/4885
US-11311637-B2 Positron emitting radionuclide labeled peptides for human uPAR PET imaging PLAUR, PLAU, SERPINE1 GPR84 384/4885FFAR1 488/4885HTR2A 3295/4885
US-20250049971-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS PLAUR, PLAU, PROKR1 GPR84 231/4885FFAR1 601/4885HTR2A 1486/4885
US-20260069728-A1 MULTI-TARGETING COMPOUND AND USE THEREOF CXCR4, CXCR2, GRPR GPR84 62/4885FFAR1 60/4885HTR2A 1276/4885
US-20250319215-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS (HNSCCS) PLAUR, PLAU, SERPINE1 GPR84 636/4885FFAR1 217/4885HTR2A 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.