SCHEMBL8985129

SCHEMBL8985129

N#CNc1cccc(NC#N)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALPG P10696 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CTSK P43235 1/20 0.35
HPGD P15428 1/20 0.34
HSD11B1 P28845 2/20 0.33
RXFP1 Q9HBX9 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
PSMB8 P28062 2/20 0.31
DUSP3 P51452 1/20 0.31
PTPN5 P54829 1/20 0.31
PTPN11 Q06124 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5565908 0.73 NCF1 (0.59) KMT2ARAB9AKDM4EHPGDHSD11B1
SCHEMBL20135758 0.72
SCHEMBL11847450 0.69 KDR (0.36) MEN1KMT2AMAPTCTSKDUSP3
SCHEMBL10965323 0.65 MEN1 (0.47) MEN1KMT2AMAPTRAB9AKDM4E
SCHEMBL8985182 0.65 ALDH1A1 (0.42) MEN1KMT2AMAPTKDM4ETDP1
SCHEMBL5839929 0.64
SCHEMBL8985146 0.63 KDM4E (0.41) MEN1KMT2AMAPTKDM4ETDP1
SCHEMBL18891533 0.63 ALDH1A1 (0.44) MEN1KMT2AMAPTRAB9AKDM4E
SCHEMBL318096 0.63 KCNH2 (0.57) MEN1KMT2AMAPTRAB9AKDM4E
SCHEMBL11050237 0.63 TSHR (0.36) KDM4EHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US claimed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US claimed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP disclosed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US disclosed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP disclosed
EP-0078039-B1 THERMOSETTING RESIN COMPOSITION, PREPOLYMER THEREOF AND CURED ARTICLE THEREOF Hitachi, Ltd. (JP) 1986-01-22 EP disclosed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US disclosed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US disclosed
EP-0123262-A2 Resin encapsulated semiconductor device and process for producing the same HITACHI, LTD. (JP) 1984-10-31 EP disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed