Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9570749 | 0.94 | KDM4E (0.57) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| Fumaric Acid SCHEMBL8985248 | 0.94 | KDM4E (0.57) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL8985169 | 0.83 | KDM4E (0.57) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL8985443 | 0.80 | KDM4E (0.59) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL24493549 | 0.76 | KDM4E (0.47) | KDM4ESMN1; SMN2KMT2ALMNATSHR | |
| SCHEMBL27339399 | 0.75 | SMN1; SMN2 (0.85) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL14503304 | 0.72 | SMN1; SMN2 (1.00) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL28685992 | 0.70 | ACHE (0.65) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL28685994 | 0.70 | ACHE (0.65) | KDM4EACHEBACE1SMN1; SMN2KMT2A | |
| SCHEMBL30915761 | 0.70 | KDM4E (0.46) | KDM4ELMNANPSR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | claimed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |