Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985153 | 0.83 | KDM4E (0.63) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL8985207 | 0.78 | SMN1; SMN2 (0.55) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| Fumaric Acid SCHEMBL9570749 | 0.78 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| Fumaric Acid SCHEMBL8985248 | 0.78 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL27339399 | 0.75 | SMN1; SMN2 (0.85) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL14503304 | 0.72 | SMN1; SMN2 (1.00) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL8985281 | 0.71 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL8985233 | 0.70 | ADRA1A (0.53) | KDM4EADRA1A | |
| SCHEMBL8132848 | 0.70 | SMN1; SMN2 (0.74) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 | |
| SCHEMBL29361009 | 0.70 | SMN1; SMN2 (0.74) | KDM4ESMN1; SMN2ALDH1A1ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | claimed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |