SCHEMBL8985165

SCHEMBL8985165

N#CNCc1cccc(CNC#N)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
CYP19A1 P11511 5/20 0.43
MAPT P10636 3/20 0.41
PKM P14618 2/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ALOX12 P18054 1/20 0.41
ATM Q13315 1/20 0.38
CYP3A4 P08684 2/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 2/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581278 0.83 MAPT (0.52) KMT2AMEN1CYP1A2CYP1A1CYP1B1
Hydrochloric Acid SCHEMBL7638290 0.81 MAPT (0.56) KMT2AMEN1CYP1A2CYP1A1CYP1B1
SCHEMBL7168830 0.79 LOXL2 (0.46) KMT2AMEN1CYP1A2CYP1A1CYP1B1
SCHEMBL10155732 0.78 TSHR (0.56) KMT2AMEN1CYP1A2CYP19A1MAPT
SCHEMBL27732887 0.77 MAOB (0.54) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL19928638 0.74 LOXL2 (0.52) CYP1A2
Propene SCHEMBL11507987 0.73 KDM4E (0.47) KMT2AMEN1CYP1A2MAPTLMNA
SCHEMBL11104488 0.73 CYP1A2 (0.62) CYP1A2MAPTPKMLMNAALDH1A1
SCHEMBL1697126 0.72 MAPT (0.64) MAPTPKMLMNAALDH1A1ALOX12
SCHEMBL6814739 0.71 CA2 (0.47) KMT2ACYP1A2MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US claimed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US claimed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
EP-0153603-B1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT, AND PRODUCTION OF CURED PRODUCT HITACHI, LTD. (JP) 1992-01-02 EP disclosed
EP-0102052-B1 HEAT-RESISTANT RESIN, THERMOSETTING COMPOSITION AFFORDING THE SAME AND PREPOLYMER THEREOF HITACHI, LTD. (JP) 1990-10-31 EP disclosed
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP disclosed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US disclosed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP disclosed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US disclosed
EP-0153603-A2 Thermosetting resin composition, cured product, and production of cured product HITACHI, LTD. (JP) 1985-09-04 EP disclosed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US disclosed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US disclosed
EP-0123262-A2 Resin encapsulated semiconductor device and process for producing the same HITACHI, LTD. (JP) 1984-10-31 EP disclosed
EP-0102052-A2 Heat-resistant resin, thermosetting composition affording the same and prepolymer thereof HITACHI, LTD. (JP) 1984-03-07 EP disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed