SCHEMBL19928638

SCHEMBL19928638

N#CNCc1ccc(CN)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 7/20 0.52
TPSAB1 Q15661 3/20 0.45
HRH3 Q9Y5N1 1/20 0.44
ABAT P80404 1/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ANPEP P15144 1/20 0.37
ERAP2 Q6P179 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
F10 P00742 1/20 0.35
F11 P03951 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7168830 0.88 LOXL2 (0.46) LOXL2CYP1A2CYP2D6CYP2C9TSHR
SCHEMBL2700839 0.77 TPSAB1 (0.45) LOXL2TPSAB1HRH3ABATCYP1A2
SCHEMBL3174859 0.77 PYCR1 (0.48) LOXL2CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL581278 0.76 MAPT (0.52) CYP1A2TSHRCA12CA2CA7
SCHEMBL8985165 0.74 KMT2A (0.46) CYP1A2
Hydrochloric Acid SCHEMBL7638290 0.74 MAPT (0.56) CYP1A2TSHRCA12CA2CA7
SCHEMBL4865180 0.73 KDM4E (0.54) LOXL2TPSAB1HRH3ABATCYP1A2
SCHEMBL10701801 0.72 ALDH1A1 (0.52) TSHRCA12CA1CA2CA7
SCHEMBL15828 0.71 HRH3 (0.79) LOXL2HRH3ABATTAAR1F10
SCHEMBL27238704 0.71 HRH3 (0.79) LOXL2HRH3ABATTAAR1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9910037-B2 Conjugation of multiple vancomycin molecules on a polyvinyl alcohol backbone for the capture of microorganisms IRIS INTERNATIONAL, INC. (US) 2018-03-06 US disclosed