Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985506 | 0.84 | APP (0.33) | APP | |
| SCHEMBL8985328 | 0.84 | PTGS1 (0.43) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985497 | 0.81 | APP (0.35) | PTGS2APP | |
| SCHEMBL8985478 | 0.80 | MAPK14 (0.48) | PTGS1PTGS2KDM4EHPGDHSD17B10 | |
| SCHEMBL8985413 | 0.78 | PTGS2 (0.71) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985332 | 0.76 | PTGS1 (0.43) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL15824911 | 0.73 | TSHR (0.42) | CYP3A4HPGDTSHRHSD17B10APP | |
| SCHEMBL8985521 | 0.70 | PTGS1 (0.30) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985252 | 0.68 | MAPK14 (0.44) | PTGS1PTGS2 | |
| SCHEMBL8985372 | 0.68 | PTGS2 (0.34) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | claimed |
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |