Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985478 | 0.85 | MAPK14 (0.48) | MAPK14OPRD1PTGS1PTGS2EP300 | |
| SCHEMBL8985328 | 0.84 | PTGS1 (0.43) | PTGS1PTGS2 | |
| SCHEMBL8985336 | 0.83 | MAPK14 (0.45) | MAPK14OPRD1PTGS1PTGS2EP300 | |
| SCHEMBL8985521 | 0.83 | PTGS1 (0.30) | PTGS1PTGS2 | |
| SCHEMBL8985372 | 0.80 | PTGS2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL8985255 | 0.79 | MAPK14 (0.45) | MAPK14OPRD1PTGS1PTGS2 | |
| SCHEMBL8985373 | 0.78 | OPRD1 (0.61) | MAPK14OPRD1PTGS1PTGS2EP300 | |
| SCHEMBL8985448 | 0.74 | OPRD1 (0.39) | MAPK14OPRD1PTGS1PTGS2EP300 | |
| SCHEMBL8985469 | 0.74 | AURKA (0.47) | OPRD1PTGS1PTGS2 | |
| SCHEMBL8985406 | 0.71 | MAPK14 (0.51) | MAPK14OPRD1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |