Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985273 | 0.86 | OPRD1 (0.67) | OPRD1L3MBTL1UBE2NEP300MAPK14 | |
| SCHEMBL8985533 | 0.86 | OPRD1 (0.64) | OPRD1L3MBTL1UBE2NEP300MAPK14 | |
| SCHEMBL8985230 | 0.83 | OPRD1 (0.60) | OPRD1L3MBTL1UBE2NEP300ATM | |
| SCHEMBL8985238 | 0.83 | OPRD1 (0.63) | OPRD1L3MBTL1UBE2NEP300ATM | |
| SCHEMBL8985492 | 0.82 | OPRD1 (0.58) | OPRD1EP300ATMPTGS1PTGS2 | |
| SCHEMBL7899259 | 0.76 | OPRD1 (0.81) | OPRD1L3MBTL1EP300MAPK14ATM | |
| SCHEMBL8985541 | 0.76 | MAPK14 (0.56) | OPRD1L3MBTL1UBE2NMAPK14NPC1 | |
| SCHEMBL9375676 | 0.76 | OPRD1 (0.56) | OPRD1L3MBTL1UBE2NEP300MAPK14 | |
| SCHEMBL8985455 | 0.73 | SLC6A4 (0.48) | OPRD1L3MBTL1UBE2NEP300ATM | |
| SCHEMBL7623155 | 0.73 | PTGS1 (0.67) | OPRD1L3MBTL1UBE2NMAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |