Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | EP300 | Q09472 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985341 | 0.91 | EP300 (0.41) | SLC6A4EP300SLC6A2SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL8985552 | 0.90 | OPRD1 (0.49) | SLC6A4EP300OPRD1SLC6A2SLC6A3 | |
| SCHEMBL8985538 | 0.85 | PTGS1 (0.51) | SLC6A4EP300CYP1A2SLC6A2SLC6A3 | |
| SCHEMBL8985236 | 0.85 | SLC6A4 (0.43) | SLC6A4EP300CYP1A2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL8985503 | 0.84 | EP300 (0.44) | EP300OPRD1PTGS2 | |
| Hydrochloric Acid SCHEMBL8985440 | 0.84 | PTGS1 (0.50) | SLC6A4EP300CYP1A2SLC6A2SLC6A3 | |
| SCHEMBL8985394 | 0.80 | PTGS1 (0.37) | SLC6A4EP300CYP1A2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL8985418 | 0.80 | PTGS2 (0.54) | OPRD1CYP1A2ATMPTGS2KDM4E | |
| SCHEMBL8985480 | 0.76 | SLC6A4 (0.43) | SLC6A4EP300SLC6A2SLC6A3HTR2A | |
| SCHEMBL8985230 | 0.76 | OPRD1 (0.60) | EP300OPRD1UBE2NL3MBTL1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |