Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985511 | 0.91 | OPRD1 (0.74) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985429 | 0.91 | KDM4E (0.50) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985273 | 0.86 | OPRD1 (0.67) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985533 | 0.86 | OPRD1 (0.64) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985326 | 0.85 | MAPK14 (0.52) | OPRD1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL8985276 | 0.85 | OPRD1 (0.66) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985425 | 0.85 | MAPK14 (0.52) | OPRD1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL8985488 | 0.85 | ALDH1A1 (0.55) | OPRD1EP300MAPTKDM4ENPC1 | |
| SCHEMBL8985230 | 0.83 | OPRD1 (0.60) | OPRD1EP300MAPTNPC1HPGD | |
| SCHEMBL8985306 | 0.83 | OPRD1 (0.60) | OPRD1EP300MAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |