Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985236 | 0.93 | SLC6A4 (0.43) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8985538 | 0.93 | PTGS1 (0.51) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL8985440 | 0.92 | PTGS1 (0.50) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8985455 | 0.91 | SLC6A4 (0.48) | EP300SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8985394 | 0.88 | PTGS1 (0.37) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8985480 | 0.83 | SLC6A4 (0.43) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8985346 | 0.82 | PTGS1 (0.48) | EP300PTGS1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8985223 | 0.81 | PTGS2 (0.50) | EP300PTGS1PTGS2MAPK14 | |
| SCHEMBL8985433 | 0.80 | PTGS2 (0.42) | EP300PTGS1PTGS2MAPK14 | |
| SCHEMBL8985330 | 0.80 | PTGS1 (0.49) | PTGS1PTGS2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |