Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985441 | 1.00 | TCF4 (0.38) | TCF4CTNNB1CES2CES1AKR1C3 | |
| SCHEMBL7627953 | 0.83 | TCF4 (0.51) | TCF4CTNNB1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7620156 | 0.83 | TCF4 (0.51) | TCF4CTNNB1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7620158 | 0.83 | TCF4 (0.51) | TCF4CTNNB1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7814039 | 0.76 | CES2 (0.50) | CES2CES1CYP1A2PLK1 | |
| SCHEMBL7088183 | 0.75 | CES2 (0.62) | CES2CES1PLK1 | |
| SCHEMBL2159392 | 0.71 | TCF4 (0.62) | TCF4CTNNB1MAPTNQO2ADORA3 | |
| SCHEMBL1848235 | 0.71 | TCF4 (0.62) | TCF4CTNNB1MAPTNQO2ADORA3 | |
| SCHEMBL8094065 | 0.70 | LMNA (0.40) | AKR1C3AKR1C2AKR1C1MAPTPTGS1 | |
| SCHEMBL8094061 | 0.70 | LMNA (0.40) | AKR1C3AKR1C2AKR1C1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |