Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985459 | 0.87 | CYP1A2 (0.37) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 | |
| SCHEMBL8985514 | 0.85 | PTGS2 (0.42) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 | |
| SCHEMBL8985336 | 0.84 | MAPK14 (0.45) | PTGS2PTGS1KDM4ERAB9ANPC1 | |
| SCHEMBL8985319 | 0.84 | PTGS2 (0.34) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 | |
| SCHEMBL8985260 | 0.83 | PTGS2 (0.65) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 | |
| SCHEMBL8985448 | 0.83 | OPRD1 (0.39) | PTGS2PTGS1KDM4ERAB9ANPC1 | |
| SCHEMBL8985328 | 0.82 | PTGS1 (0.43) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 | |
| SCHEMBL8985524 | 0.80 | MAPK14 (0.51) | PTGS2PTGS1KDM4EHPGDTSHR | |
| SCHEMBL24035226 | 0.78 | MEN1 (0.49) | CYP1A2CYP2C9CYP2C19CYP3A4KDM4E | |
| SCHEMBL8985493 | 0.77 | PTGS1 (0.41) | PTGS2CYP1A2CYP2C9CYP2C19PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |