Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164440 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2POLBKDM4ELMNA | |
| SCHEMBL1754863 | 0.75 | ALDH1A1 (0.39) | POLBKDM4ELMNAMAPTHTT | |
| SCHEMBL28246060 | 0.74 | GABRA1 (0.42) | GABRA1GABRB2POLBKDM4ELMNA | |
| SCHEMBL11555510 | 0.74 | GABRA1 (0.45) | GABRA1GABRB2KDM4ELMNAMAPT | |
| SCHEMBL8801626 | 0.73 | ALDH1A1 (0.36) | POLBKDM4ELMNAMAPTHTT | |
| SCHEMBL14321847 | 0.72 | GABRA1 (0.44) | GABRA1GABRB2KDM4ELMNAMAPT | |
| SCHEMBL3646580 | 0.72 | GABRA1 (0.40) | GABRA1GABRB2POLBKDM4ELMNA | |
| SCHEMBL7775721 | 0.71 | GABRA1 (0.42) | GABRA1GABRB2KDM4ELMNAMAPT | |
| SCHEMBL3806685 | 0.71 | GABRA1 (0.42) | GABRA1GABRB2KDM4ELMNAMAPT | |
| SCHEMBL9816019 | 0.70 | GABRA1 (0.43) | GABRA1GABRB2POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | claimed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |