Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986861 | 0.89 | TRPA1 (0.52) | POLBNPC1KDRKMT2AALDH1A1 | |
| SCHEMBL8986897 | 0.85 | KMT2A (0.48) | POLBKMT2ARAB9A | |
| SCHEMBL8986884 | 0.79 | TRPA1 (0.42) | POLBNPC1KMT2AALDH1A1TRPA1 | |
| SCHEMBL8986883 | 0.78 | KMT2A (0.70) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL8986829 | 0.74 | PLA2G7 (0.44) | NPC1KDRKMT2AALDH1A1MAPT | |
| Acetic Acid SCHEMBL8986878 | 0.73 | PLA2G7 (0.41) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL8986852 | 0.69 | SMN1; SMN2 (0.58) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL11406650 | 0.68 | TRPA1 (0.45) | POLBNPC1EGFRTRPA1 | |
| SCHEMBL11406646 | 0.68 | TRPA1 (0.45) | POLBNPC1EGFRTRPA1 | |
| SCHEMBL23231088 | 0.68 | HTR1A (0.48) | ALDH1A1TRPA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0572782-A1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |