Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986884 | 0.90 | TRPA1 (0.42) | TRPA1CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL8986885 | 0.89 | POLB (0.47) | TRPA1CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL8986882 | 0.85 | ALDH1A1 (0.46) | CYP1A2CYP3A4NPC1CNR1LMNA | |
| SCHEMBL8986829 | 0.85 | PLA2G7 (0.44) | CYP1A2CYP3A4CYP2C19TSHRNPC1 | |
| Acetic Acid SCHEMBL8986878 | 0.84 | PLA2G7 (0.41) | CYP1A2CYP3A4CYP2C19TSHRNPC1 | |
| SCHEMBL8986845 | 0.78 | SMN1; SMN2 (0.59) | CYP1A2CYP3A4CYP2C19TSHRNPC1 | |
| SCHEMBL8986897 | 0.74 | KMT2A (0.48) | POLBMEN1KMT2ARAB9A | |
| SCHEMBL8986838 | 0.73 | NPC1 (0.62) | CYP1A2CYP3A4CYP2C19TSHRNPC1 | |
| SCHEMBL8986852 | 0.69 | SMN1; SMN2 (0.58) | CYP1A2CYP3A4CYP2C19NPC1POLB | |
| SCHEMBL11406646 | 0.68 | TRPA1 (0.45) | TRPA1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0572782-A1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |