Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8987017

CCCCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccc([N+](=O)[O-])cc1.[Cl-]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.61
HSP90AA1 P07900 1/20 0.61
MMP2 P08253 1/20 0.61
MC4R P32245 1/20 0.61
RAD52 P43351 1/20 0.61
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
TP53 P04637 1/20 0.60
MAPK1 P28482 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HTT P42858 2/20 0.59
DNM1 Q05193 2/20 0.58
KCNH2 Q12809 1/20 0.50
ALDH1A1 P00352 2/20 0.49
MAPT P10636 1/20 0.43
CHRNA7 P36544 1/20 0.43
HTR3A P46098 1/20 0.43
MGLL Q99685 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11440808 1.00 PSMD14 (0.61) PSMD14HSP90AA1MMP2MC4RRAD52
SCHEMBL8815105 0.98 DNM1 (0.59) PSMD14HSP90AA1MMP2MC4RRAD52
Hydrochloric Acid SCHEMBL8720973 0.84 HSP90AA1 (0.83) PSMD14HSP90AA1MMP2MC4RRAD52
Hydrochloric Acid SCHEMBL7764496 0.84 HSP90AA1 (0.83) PSMD14HSP90AA1MMP2MC4RRAD52
Hydrochloric Acid SCHEMBL7760909 0.84 HSP90AA1 (0.83) PSMD14HSP90AA1MMP2MC4RRAD52
Hydrochloric Acid SCHEMBL10943210 0.84 HSP90AA1 (0.83) PSMD14HSP90AA1MMP2MC4RRAD52
Hydrochloric Acid SCHEMBL8719712 0.84 HSP90AA1 (0.83) PSMD14HSP90AA1MMP2MC4RRAD52
Cetalkonium SCHEMBL14965243 0.82 DNM1 (0.81) PSMD14HSP90AA1MMP2MC4RRAD52
SCHEMBL28353782 0.82 DNM1 (0.81) PSMD14HSP90AA1MMP2MC4RRAD52
Acetic Acid SCHEMBL7764904 0.81 DNM1 (0.65) PSMD14HSP90AA1MMP2MC4RRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4912009-A Fusible styrene-acrylic copolymer EASTMAN KODAK COMPANY (US) 1990-03-27 US claimed
US-4684596-A Electrographic toner and developer composition containing quaternary ammonium salt charge-control agent EASTMAN KODAK COMPANY (US) 1987-08-04 US claimed
US-5516615-A ELECTROSTATICS FOR ELECTROGRAPHY AND DEVELOPERS EASTMAN KODAK COMPANY (US) 1996-05-14 US disclosed
EP-0376202-B1 Electrostatographic toners and method of making EASTMAN KODAK CO (US) 1994-06-01 EP disclosed
EP-0321363-B1 NEW ELECTROSTATOGRAPHIC TONERS AND DEVELOPERS CONTAINING NEW CHARGE-CONTROL AGENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-03-31 EP disclosed
EP-0495071-A1 TONERS AND DEVELOPERS CONTAINING N-SUBSTITUTED PYRIDINIUM SALTS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1992-07-22 EP disclosed
WO-1992002860-A1 TONERS AND DEVELOPERS CONTAINING N-SUBSTITUTED PYRIDINIUM SALTS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1992-02-20 WO disclosed
EP-0376202-A2 Electrostatographic toners and method of making EASTMAN KODAK COMPANY (US) 1990-07-04 EP disclosed
US-4912009-A Fusible styrene-acrylic copolymer EASTMAN KODAK COMPANY (US) 1990-03-27 US disclosed
EP-0321363-A2 New electrostatographic toners and developers containing new charge-control agents EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-06-21 EP disclosed
US-4684596-A Electrographic toner and developer composition containing quaternary ammonium salt charge-control agent EASTMAN KODAK COMPANY (US) 1987-08-04 US disclosed