Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987409 | 0.86 | PPARG (0.50) | LTB4RPPARGKDM4EMAPT | |
| SCHEMBL8987461 | 0.83 | ALDH1A1 (0.50) | PTPN1NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL8987362 | 0.81 | LTB4R (0.58) | PTPN1CYSLTR2CYSLTR1LTB4RNPC1 | |
| SCHEMBL4310750 | 0.74 | HDAC3 (0.65) | CYSLTR2CYSLTR1FAAH | |
| SCHEMBL8987309 | 0.74 | LTB4R (0.79) | LTB4R | |
| SCHEMBL8986940 | 0.74 | LTB4R (0.75) | LTB4RPDE5ATOP2A | |
| SCHEMBL9291792 | 0.74 | LTB4R (0.75) | LTB4RPDE5ATOP2A | |
| SCHEMBL8987489 | 0.74 | LTB4R (0.75) | LTB4RPDE5ATOP2A | |
| SCHEMBL8986999 | 0.73 | LTB4R (0.73) | LTB4R | |
| SCHEMBL19474670 | 0.72 | LTA4H (0.53) | CYSLTR2CYSLTR1PPARGMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |