Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291603 | 0.80 | LTB4R (0.58) | LTB4RALDH1A1HPGDPDE4B | |
| SCHEMBL8987130 | 0.80 | LTB4R (0.58) | LTB4RALDH1A1HPGDPDE4B | |
| SCHEMBL5365533 | 0.71 | GAA (0.51) | GAAMAPTALDH1A1HPGDPTGDR2 | |
| SCHEMBL8987100 | 0.70 | ALDH2 (0.46) | LTB4RGAATBXAS1PTGS2 | |
| SCHEMBL8987216 | 0.70 | ALDH2 (0.46) | LTB4RGAATBXAS1PTGS2 | |
| SCHEMBL8987182 | 0.68 | LTB4R (0.52) | LTB4RGAAALDH1A1HPGDPDE4B | |
| SCHEMBL5720595 | 0.67 | NPC1 (0.42) | MAPTALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL9391332 | 0.66 | PDE4B (0.57) | PDE4BTBXAS1 | |
| SCHEMBL9862463 | 0.65 | PDE4B (0.52) | LTB4RALDH1A1PDE4BTBXAS1 | |
| SCHEMBL7832869 | 0.65 | PDE4B (0.55) | LTB4RGAAPDE4BTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |