Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 13/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291603 | 1.00 | LTB4R (0.58) | LTB4RPPARGPPARAFFAR1PPARD | |
| SCHEMBL8987100 | 0.86 | ALDH2 (0.46) | LTB4RPTPN1 | |
| SCHEMBL8987216 | 0.86 | ALDH2 (0.46) | LTB4RPTPN1 | |
| SCHEMBL5407468 | 0.86 | LTB4R (0.62) | LTB4RFABP3FABP4 | |
| SCHEMBL8987182 | 0.82 | LTB4R (0.52) | LTB4RPPARGPPARAFFAR1PPARD | |
| SCHEMBL8987396 | 0.80 | LTB4R (0.41) | LTB4RPDE4BALDH1A1HPGD | |
| SCHEMBL8987240 | 0.76 | LTB4R (0.93) | LTB4R | |
| SCHEMBL5365533 | 0.76 | GAA (0.51) | FFAR1ALDH1A1HPGD | |
| SCHEMBL4298103 | 0.76 | PPARA (0.68) | LTB4RPPARGPPARAFFAR1PPARD | |
| SCHEMBL1801957 | 0.76 | PPARA (0.68) | LTB4RPPARGPPARAFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |