SCHEMBL8987708

SCHEMBL8987708

CC(=O)N(c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)c1ccncn1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.41
KDR P35968 5/20 0.40
BRAF P15056 3/20 0.40
MAPK14 Q16539 3/20 0.40
TNNI3K Q59H18 3/20 0.40
KDM4C Q9H3R0 1/20 0.39
LIPE Q05469 4/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
SCN9A Q15858 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAOB P27338 1/20 0.36
LMNA P02545 1/20 0.36
TEK Q02763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987954 0.84 KDM4C (0.39) KDM4CSCN9AMEN1KMT2AMAOB
SCHEMBL8987790 0.82 LIPE (0.40) CSF1RBRAFKDM4CLIPEMMP2
SCHEMBL8987860 0.81 SCN9A (0.38) CSF1RBRAFKDM4CLIPEMMP2
SCHEMBL8988022 0.80 MMP2 (0.38) CSF1RBRAFKDM4CLIPEMMP2
SCHEMBL8987662 0.80 MMP2 (0.38) CSF1RBRAFMAPK14LIPEMMP2
SCHEMBL8987993 0.78 SCN9A (0.37) KDRBRAFLIPEMMP2MMP9
SCHEMBL8987909 0.78 MAOB (0.37) CSF1RBRAFMAPK14KDM4CLIPE
SCHEMBL8987689 0.76 MMP2 (0.38) CSF1RBRAFKDM4CMMP2MMP9
SCHEMBL8987785 0.76 PROKR1 (0.38) CSF1RKDRBRAFLIPEMMP2
SCHEMBL7985479 0.76 POLQ (0.47) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556859-A N-(4-pyrimidinyl)amide pesticides DOWELANCO (US) 1996-09-17 US disclosed