Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.72 |
| ▸ | GSK3A | P49840 | 3/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.67 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.67 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987764 | 0.83 | RIOK2 (0.51) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8987914 | 0.81 | CACNA1H (0.48) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8987842 | 0.80 | SMN1; SMN2 (0.56) | RIOK2GSK3AMAPK10L3MBTL1HDAC6 | |
| SCHEMBL8987776 | 0.79 | CACNA1H (0.48) | RIOK2MEN1KMT2ANLRP3 | |
| SCHEMBL8987928 | 0.78 | TRPV1 (0.54) | RIOK2MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL8987871 | 0.78 | ALDH1A1 (0.53) | MAPK10MAPK8MEN1KMT2ACCNA2 | |
| SCHEMBL8987834 | 0.78 | KMT2A (0.51) | RIOK2GSK3AMAPK10MAPK8L3MBTL1 | |
| SCHEMBL8987866 | 0.78 | ALDH1A1 (0.46) | RIOK2MAPK10ANO1L3MBTL1MEN1 | |
| SCHEMBL8987643 | 0.77 | MAPK10 (0.46) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL8987813 | 0.77 | ALDH1A1 (0.49) | RIOK2GSK3AMAPK10MAPK8HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |