Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987863 | 0.92 | MPO (0.57) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL11008112 | 0.87 | CA12 (0.59) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL11009308 | 0.85 | CA12 (0.61) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL14560540 | 0.83 | MPO (0.57) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL8987759 | 0.82 | FEN1 (0.57) | CA12MEN1ALDH1A1KMT2AMPO | |
| SCHEMBL8987944 | 0.82 | KMT2A (0.53) | MEN1ALDH1A1KMT2APOLBPKM | |
| SCHEMBL8987676 | 0.82 | POLB (0.47) | CA12MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL7016344 | 0.81 | CA12 (0.56) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL1662185 | 0.78 | ALDH1A1 (0.68) | CA12CA9MEN1ALDH1A1KMT2A | |
| SCHEMBL9049869 | 0.78 | CA12 (0.60) | CA12CA9MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306721-A | Immunostimulants, viricides | ARZNEIMITTELERK DRESDEN G.M.B.H. (DE) | 1994-04-26 | — | — | US | claimed |
| EP-0454060-B1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | DROESSLER KARL PROF DR (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5306721-A | Immunostimulants, viricides | ARZNEIMITTELERK DRESDEN G.M.B.H. (DE) | 1994-04-26 | — | — | US | disclosed |
| EP-0454060-A1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-10-30 | — | — | EP | disclosed |