Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987811 | 0.89 | TSHR (0.40) | SCN9AMAPK14PTGIR | |
| SCHEMBL8987993 | 0.86 | SCN9A (0.37) | MMP2MMP9SCN9A | |
| SCHEMBL8987729 | 0.85 | TSHR (0.41) | SCN9AMAPK14TNK2PTGIR | |
| SCHEMBL8987840 | 0.82 | MMP2 (0.40) | GAAMMP2MMP9MT-CO2NPSR1 | |
| SCHEMBL8987785 | 0.82 | PROKR1 (0.38) | MMP2MMP9SCN9ATNK2 | |
| SCHEMBL8987794 | 0.81 | CACNA1G (0.37) | SCN9ALMNARAB9AALDH1A1 | |
| SCHEMBL8987900 | 0.80 | MAPK14 (0.38) | GAAMMP2MMP9MT-CO2NPSR1 | |
| SCHEMBL8987839 | 0.80 | MMP2 (0.41) | GAAMMP2MMP9MT-CO2NPSR1 | |
| SCHEMBL8988077 | 0.78 | TNK2 (0.46) | MAPK14TNK2 | |
| SCHEMBL8988017 | 0.77 | SCN9A (0.37) | NPSR1SCN9ALMNARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |