Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987884 | 0.78 | RIOK2 (0.72) | MEN1KMT2ACDK5CDK5R1MAPK10 | |
| SCHEMBL29409209 | 0.76 | POLB (0.56) | ALDH1A1KDM4EMEN1KMT2AGSK3B | |
| SCHEMBL14520097 | 0.74 | MEN1 (0.66) | ALDH1A1KDM4EMEN1KMT2AMAPK10 | |
| SCHEMBL28692610 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPK10 | |
| SCHEMBL10082886 | 0.72 | SMN1; SMN2 (0.60) | ALDH1A1KDM4EMAPK8MAPK9LMNA | |
| SCHEMBL3424958 | 0.72 | CCNA2 (0.62) | ALDH1A1KDM4EMEN1KMT2AGSK3B | |
| SCHEMBL10082487 | 0.72 | TYK2 (0.41) | ALDH1A1KDM4EMEN1KMT2AMAPK8 | |
| SCHEMBL8987776 | 0.72 | CACNA1H (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8987914 | 0.72 | CACNA1H (0.48) | KMT2AMAPK10MAPK8SMN1; SMN2 | |
| SCHEMBL1947868 | 0.71 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |