Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 12/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988013 | 0.83 | RIOK2 (0.48) | CACNA1HNLRP3RIOK2SMN1; SMN2 | |
| SCHEMBL8987914 | 0.82 | CACNA1H (0.48) | CACNA1HNLRP3RIOK2CACNA1GCACNA1I | |
| SCHEMBL8987928 | 0.81 | TRPV1 (0.54) | RIOK2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL8987842 | 0.81 | SMN1; SMN2 (0.56) | CACNA1HRIOK2CACNA1GCACNA1IRAB9A | |
| SCHEMBL8987643 | 0.80 | MAPK10 (0.46) | CACNA1HRIOK2CACNA1GCACNA1ICACNA1C | |
| SCHEMBL8987764 | 0.80 | RIOK2 (0.51) | CACNA1HRIOK2CACNA1GCACNA1IRAB9A | |
| SCHEMBL8987881 | 0.79 | SMN1; SMN2 (0.45) | CACNA1HRIOK2CACNA1GCACNA1ISMN1; SMN2 | |
| SCHEMBL8987884 | 0.79 | RIOK2 (0.72) | NLRP3RIOK2MEN1KMT2A | |
| SCHEMBL8987834 | 0.79 | KMT2A (0.51) | RIOK2RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL8987866 | 0.79 | ALDH1A1 (0.46) | RIOK2RAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |