Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30252114 | 1.00 | LMNA (0.38) | LMNACSNK2A1GABRA1GABRB2TRPA1 | |
| SCHEMBL17861690 | 0.83 | RXRA (0.42) | LMNACSNK2A1TRPA1PTGS1CACNA1C | |
| SCHEMBL28606337 | 0.83 | LMNA (0.40) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL26879496 | 0.83 | ALDH1A1 (0.43) | LMNACSNK2A1TRPA1PTGS1CACNA1C | |
| SCHEMBL11063120 | 0.83 | LMNA (0.40) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL739698 | 0.81 | HDAC4 (0.48) | ALDH1A1GAAHDAC4HDAC8SMN1; SMN2 | |
| SCHEMBL3365122 | 0.79 | LMNA (0.47) | LMNACSNK2A1TRPA1PTGS1CACNA1C | |
| SCHEMBL9945998 | 0.79 | LMNA (0.45) | LMNACSNK2A1TRPA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3191477 | 0.79 | GABRA1 (0.41) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL28852756 | 0.79 | LMNA (0.34) | LMNAGABRA1GABRB2TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511947-B1 | Process for the purification of 2,6-diisopropyl phenol | LEIRAS OY (FI) | 1996-07-10 | — | — | EP | claimed |
| US-20230174444-A1 | PROCESS FOR THE PREPARATION OF PROPOFOL | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2023-06-08 | — | — | US | disclosed |
| EP-4126803-A1 | PROCESS FOR THE PREPARATION OF PROPOFOL | Fresenius Kabi Oncology Limited (IN) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021191832-A1 | PROCESS FOR THE PREPARATION OF PROPOFOL | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2021-09-30 | — | — | WO | disclosed |
| EP-2516369-B1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LTD (IN) | 2015-07-22 | — | — | EP | disclosed |
| US-8664452-B2 | Process for preparing extra pure 2, 6-diisopropyl phenol | HARMAN FINOCHEM LIMITED (US) | 2014-03-04 | — | — | US | disclosed |
| EP-2522651-B1 | Process for the purification of 2,6-diisopropyl phenol | SIEGFRIED AG (CH) | 2013-11-20 | — | — | EP | disclosed |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2013-03-21 | — | — | US | disclosed |
| WO-2013035103-A1 | PHENOL C-ALKYLATION PROCESS | DAVULURI RAMAMOHANRAO (IN) | 2013-03-14 | — | — | WO | disclosed |
| WO-2012152665-A1 | PROCESS FOR THE PURIFICATION OF 2,6-DIISOPROPYL PHENOL | SIEGFRIED AG (CH) | 2012-11-15 | — | — | WO | disclosed |
| EP-2522651-A1 | Process for the purification of 2,6-diisopropyl phenol | Siegfried AG (CH) | 2012-11-14 | — | — | EP | disclosed |
| EP-2516369-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | Harman Finochem Limited (IN) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011161687-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |
| US-7884234-B2 | N-[4-(tert-butyl)benzyl]-N-[4 -(trifluoromethoxy)biphenyl-3-yl]oxamic Acid; Inhibitors of plasminogen activator inhibitor-1 (PAI-1); thrombogenesis, fibrogenesis, accumulation of visceral fat, cell proliferation, angiogenesis | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20090215899-A9 | N-Phenyloxamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-08-27 | — | — | US | disclosed |
| US-20080249175-A1 | N-Phenyloxamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-10-09 | — | — | US | disclosed |
| EP-0511947-B1 | Process for the purification of 2,6-diisopropyl phenol | LEIRAS OY (FI) | 1996-07-10 | — | — | EP | disclosed |
| US-5175376-A | PROCESS FOR THE PURIFICATION OF 2,6-DIISOPROPYL PHENOL | LEIRAS OY (FI) | 1992-12-29 | — | — | US | disclosed |
| EP-0511947-A1 | Process for the purification of 2,6-diisopropyl phenol | LEIRAS OY (FI) | 1992-11-04 | — | — | EP | disclosed |
| US-4267394-A | SELECTIVE TO THE ORTHO POSITION, USING A COMPLEX OF BORON TRIFLUORIDE WITH A DIALKYL ETHER TO CATALYZE THE REACTION | PHILLIPS PETROLEUM COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249175-A1 | N-Phenyloxamide derivatives | SERPINE1, SERPINH1, F12 | LMNA 488/4885CSNK2A1 1930/4885GABRA1 3775/4885 |
| US-20090215899-A9 | N-Phenyloxamide derivatives | SERPINE1, SERPINH1, F12 | LMNA 488/4885CSNK2A1 1930/4885GABRA1 3775/4885 |
| US-20230174444-A1 | PROCESS FOR THE PREPARATION OF PROPOFOL | CYP3A4, CYP3A5, GABARAPL1 | LMNA 3070/4885CSNK2A1 2461/4885GABRA1 18/4885 |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | CYP2B6, CYP2D6, CYP2A6 | LMNA 2537/4885CSNK2A1 2496/4885GABRA1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.