SCHEMBL898837

SCHEMBL898837

CCCC(Cl)C(Cl)(Cl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 3/20 0.34
CYP3A4 P08684 2/20 0.34
NFKB1 P19838 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
GRIK1 P39086 1/20 0.32
SLC1A3 P43003 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3369505 0.87 CA2 (0.42) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL3368465 0.85 GPR84 (0.44) GRIK1SLC1A2SLC1A1GRIK2GPR84
SCHEMBL3368152 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3371126 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL10888744 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3368426 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3371201 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3370882 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3368526 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2
SCHEMBL3370138 0.84 GPR84 (0.47) TSHRALDH1A1GRIK1GRIK2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260598-A High-strength aerogel for heat insulation material and preparation method thereof 陈柳英 2022-11-01 CN claimed
US-10597314-B2 Fatty acid biodispersant and methods of use GENERAL ELECTRIC COMPANY (US) 2020-03-24 US claimed
EP-2173670-B1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS GEN ELECTRIC (US) 2017-08-16 EP claimed
US-20160280570-A1 FATTY ACID BIODISPERSANT AND METHODS OF USE BL TECHNOLOGIES, INC. 2016-09-29 US claimed
EP-3071524-A1 FATTY ACID BIODISPERSANT AND METHODS OF USE General Electric Company (US) 2016-09-28 EP claimed
US-8784659-B2 Method for controlling microbial biofilm in aqueous systems GENERAL ELECTRIC COMPANY (US) 2014-07-22 US claimed
WO-2012044409-A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS GENERAL ELECTRIC COMPANY (US) 2012-04-05 WO claimed
US-20110052656-A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS GENERAL ELECTRIC COMPANY (US) 2011-03-03 US claimed
US-20110052655-A1 METHODS AND VESICLES FOR CONTROLLING PROTOZOA GENERAL ELECTRIC COMPANY 2011-03-03 US claimed
US-7824557-B2 Method for controlling microbial biofilm in aqueous systems GENERAL ELECTRIC COMPANY (US) 2010-11-02 US claimed
EP-2173670-A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS General Electric Company (US) 2010-04-14 EP claimed
WO-2009020694-A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS GENERAL ELECTRIC COMPANY (US) 2009-02-12 WO claimed
US-20090039035-A1 METHOD FOR CONTROLLING MICROBIAL BIOFLIM IN AQUEOUS SYSTEMS BL TECHNOLOGIES, INC. 2009-02-12 US claimed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
CN-115260598-A High-strength aerogel for heat insulation material and preparation method thereof 陈柳英 2022-11-01 CN disclosed
CN-115260598-A High-strength aerogel for heat insulation material and preparation method thereof 陈柳英 2022-11-01 CN disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed
US-4009203-A REACTION PRODUCT OF TIN HALIDE WITH A CARBOXYLIC ACID AS CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110052655-A1 METHODS AND VESICLES FOR CONTROLLING PROTOZOA CTRL, LIPA, EXOSC9 CHRM1 4716/4885AKR1A1 4435/4885CHRM3 4314/4885
US-20110052656-A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS PGLS, PLTP, PHOSPHO1 CHRM1 4010/4885AKR1A1 4792/4885CHRM3 3784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.