Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.57 |
| ▸ | NOS1 | P29475 | 3/20 | 0.57 |
| ▸ | NOS2 | P35228 | 3/20 | 0.57 |
| ▸ | GABRP | O00591 | 2/20 | 0.55 |
| ▸ | GABRD | O14764 | 2/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.55 |
| ▸ | GABRE | P78334 | 2/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600990 | 0.84 | NOS3 (0.57) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL4134209 | 0.79 | NOS3 (0.61) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL16502197 | 0.79 | NR3C2 (0.51) | MAOAMAOBNR3C2KDM4ESMN1; SMN2 | |
| SCHEMBL4543342 | 0.79 | NR3C2 (0.59) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL23706252 | 0.78 | NR3C2 (0.51) | MAOAMAOBNR3C2CYP2A6HTR2A | |
| SCHEMBL18476749 | 0.78 | NOS3 (0.59) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL318128 | 0.78 | NOS3 (0.59) | NOS3NOS1NOS2GABRPGABRD | |
| Hydrochloric Acid SCHEMBL29481452 | 0.78 | NOS3 (0.59) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL105611 | 0.78 | NOS2 (0.70) | NOS3NOS1NOS2GABRPGABRD | |
| Hydrochloric Acid SCHEMBL6953232 | 0.78 | NOS3 (0.59) | NOS3NOS1NOS2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527796-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | CHEMISCH PHARMAZEUTISCHE FORSCHUNGSGESELLSCHAFT M.B.H. (AT) | 1996-06-18 | — | — | US | disclosed |
| EP-0576906-A1 | Thienothiazine derivatives, process for their preparation and their use as antiinflammatory and analgesic agents | Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. (AT) | 1994-01-05 | — | — | EP | disclosed |