Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635466 | 0.86 | PKM (0.56) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2402894 | 0.85 | LMNA (0.67) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7640139 | 0.79 | KMT2A (0.68) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29362070 | 0.79 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL125249 | 0.79 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27763159 | 0.79 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9494228 | 0.77 | MEN1 (0.97) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9967917 | 0.77 | PKM (0.66) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30354024 | 0.77 | PKM (0.66) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9494222 | 0.77 | MAPT (0.73) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569668-A | NEMATOPHIN: 3-INDOLEETHYL-3-METHYL-2-OXO-PENTANAMIDE; ANTIBIOTICS | WELICHEM TECHNOLOGY CORPORATION (CA) | 1996-10-29 | — | — | US | disclosed |