Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.60 |
| ▸ | FNTB | P49356 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354024 | 1.00 | PKM (0.66) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL21479833 | 0.90 | MAPT (0.72) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL29407882 | 0.90 | MAPT (0.72) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL15281778 | 0.85 | MAPT (0.66) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL16982043 | 0.84 | MTNR1A (0.62) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL10031559 | 0.84 | MAPT (0.62) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2796753 | 0.83 | MAPT (0.64) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL468399 | 0.83 | MEN1 (0.68) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL29629485 | 0.83 | MEN1 (0.68) | PKMMEN1KMT2AMAPTKDM4E | |
| SCHEMBL28762416 | 0.82 | MAPT (0.67) | PKMMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442971-B1 | ESTROGEN RECEPTOR MODULATORS | RECURIUM IP HOLDINGS LLC (US) | 2024-09-25 | — | — | EP | disclosed |
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. | 2023-04-20 | — | — | US | disclosed |
| CN-112679495-B | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113717170-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20210348139-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-11-11 | — | — | US | disclosed |
| US-20210330651-A1 | ESTROGEN RECEPTOR MODULATORS | RECURIUM IP HOLDINGS, LLC | 2021-10-28 | — | — | US | disclosed |
| CN-109311870-B | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-09-21 | — | — | CN | disclosed |
| US-11065233-B2 | Estrogen receptor modulators | RECURIUM IP HOLDINGS, LLC (US) | 2021-07-20 | — | — | US | disclosed |
| US-11065234-B2 | Estrogen receptor modulators | RECURIUM IP HOLDINGS, LLC (US) | 2021-07-20 | — | — | US | disclosed |
| CN-112745316-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-05-04 | — | — | CN | disclosed |
| US-9139821-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139821-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150072383-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-03-12 | — | — | US | disclosed |
| US-20150072383-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-03-12 | — | — | US | disclosed |
| WO-2013142770-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | CODEXIS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20120152356-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND DYE-SENSITIZED SOLAR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20100158862-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2010-06-24 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| EP-1286966-B1 | 4-AMINOPIPERIDINE DERIVATIVES AND THEIR USE AS MEDICINE | SOD CONSEILS RECH APPLIC (FR) | 2008-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11065233-B2 | Estrogen receptor modulators | ESR2, GPER1, ESRRG | PKM 1904/4885MEN1 3935/4885KMT2A 3296/4885 |
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | PKM 1158/4885MEN1 3029/4885KMT2A 1017/4885 |
| US-20120165309-A1 | HETERO RING DERIVATIVE | IL2, PIK3R2, IL2RA | PKM 4499/4885MEN1 4630/4885KMT2A 1656/4885 |
| US-20100158862-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | PKM 3874/4885MEN1 4867/4885KMT2A 4516/4885 |
| US-20210330651-A1 | ESTROGEN RECEPTOR MODULATORS | ESR2, GPER1, ESRRG | PKM 1904/4885MEN1 3935/4885KMT2A 3296/4885 |
| US-11065234-B2 | Estrogen receptor modulators | ESR2, GPER1, ESRRG | PKM 1904/4885MEN1 3935/4885KMT2A 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.