Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8989860 | 0.80 | KCNA5 (0.39) | SIGMAR1THRBKCNA5SCN5AOPRK1 | |
| SCHEMBL7799100 | 0.76 | KCNA5 (0.41) | SIGMAR1KCNA5SCN5ACYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL7803104 | 0.75 | KCNA5 (0.40) | SIGMAR1KCNA5SCN5ACYP3A4TSHR | |
| SCHEMBL8989847 | 0.70 | OPRM1 (0.43) | OPRK1OPRM1 | |
| SCHEMBL7799090 | 0.69 | OPRM1 (0.40) | SIGMAR1KCNA5SCN5AOPRK1OPRM1 | |
| SCHEMBL8989835 | 0.69 | UTS2R (0.47) | OPRK1OPRM1HRH3 | |
| Hydrochloric Acid SCHEMBL8989821 | 0.68 | UTS2R (0.47) | OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL7798770 | 0.68 | OPRM1 (0.41) | KCNA5SCN5AOPRK1OPRM1 | |
| SCHEMBL7799084 | 0.67 | OPRM1 (0.40) | SIGMAR1KCNA5SCN5AOPRK1OPRM1 | |
| SCHEMBL7800794 | 0.67 | HTR7 (0.39) | SIGMAR1KCNA5SCN5AOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-A1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1996-07-10 | — | — | EP | claimed |
| WO-1995008544-A1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1995-03-30 | — | — | WO | claimed |