Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653654 | 0.87 | CASP6 (0.35) | CASP6ALKBH5NOX4TSHRGAA | |
| SCHEMBL11496671 | 0.86 | ALKBH5 (0.40) | CASP6ALKBH5TSHRGAAHTR6 | |
| SCHEMBL10915383 | 0.81 | TSHR (0.52) | ALKBH5TSHRCTSAALDH1A1HSD17B10 | |
| SCHEMBL10698670 | 0.79 | ALDH1A1 (0.53) | ALKBH5NOX4TSHRGAAALDH1A1 | |
| SCHEMBL393039 | 0.79 | ALDH1A1 (0.53) | ALKBH5NOX4TSHRGAAALDH1A1 | |
| SCHEMBL8990127 | 0.79 | ALKBH5 (0.54) | ALKBH5TSHRCTSAMEN1KMT2A | |
| SCHEMBL8990104 | 0.78 | ALKBH5 (0.49) | ALKBH5CTSA | |
| SCHEMBL693103 | 0.76 | ALKBH5 (0.64) | ALKBH5TSHRCTSAALDH1A1HSD17B10 | |
| SCHEMBL10400767 | 0.76 | ALDH1A1 (0.47) | ALKBH5TSHRHTR6ALDH1A1HSD17B10 | |
| SCHEMBL11530596 | 0.75 | TSHR (0.43) | ALKBH5TSHRCTSAHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35359-E | Amine salts of azo pigments based on pyrazolone derivatives | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0241413-B1 | AMINE SALTS OF AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |
| US-5151505-A | Monoazo dyes containing hydroxypyrazole groups | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-4992495-A | Yellow pigment | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4980458-A | Mixed sodium, ammonium and/or calcium salt crystals of laked monoazo disulfonated pyrazolone pigments | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0241413-A2 | Amine salts of azo compounds | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |