Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201609 | 0.92 | GABRA1 (0.57) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL28119481 | 0.90 | GABRA1 (0.55) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL30034858 | 0.82 | HSD17B2 (0.43) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL18668266 | 0.82 | HSD17B2 (0.43) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL19732817 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL931756 | 0.80 | ALDH1A1 (0.50) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL70807 | 0.79 | CYP2C19 (0.53) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL675962 | 0.78 | CA2 (0.58) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL18746058 | 0.78 | CHEK1 (0.50) | GABRA1GABRB2ESR1ESR2CA2 | |
| SCHEMBL29836296 | 0.78 | CYP2C9 (0.68) | GABRA1GABRB2ESR1ESR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273013-B2 | Substituted phenols as stabilizers | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| US-5427701-A | Heat and oxidation resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5376290-A | For elastomers; heat and oxidation resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5008459-A | For elastomers; registance to heat aging | CIBA-GEIGY CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0273013-A1 | Substituted phenols as stabilizers | CIBA-GEIGY AG (CH) | 1988-06-29 | — | — | EP | disclosed |